Though Cooper wants to keep the focus on finding Red, when Liz is asked to be the FBI liaison after the Good Samaritan Killer strikes again, she convinces him that attaching herself to the case will draw Red out. While Liz struggles to find a connection between the serial killer’s victims, Red calls to check in and suggests looking at his methods of torture instead. Finding that the latest victim died of the same type of injuries that she inflicted on her own son, Liz realizes that the killer is targeting people who are physically abusing family members. As Karl Hoffman, the Good Samaritan Killer, targets his next victim at a recovery group for domestic abusers, Liz discovers that all the victims were treated at hospitals where he was on duty as a nurse. Meanwhile, Red sets out to kill everyone involved in his attempted assassination.
As the FBI closes in, Hoffman takes his next victim, George Wilkinson, back to the house where he was abused as a child. As the evidence points to Wilkinson as the next target, his wife leads Liz and Ressler to the support group where he met Hoffman. Meanwhile, as the Blacklist team is targeted in the search for a mole inside the FBI, Aram is framed for arrest. But when Red kidnaps him and insists he use his computer skills to steal $5 million from a bank account, Aram’s meticulous work in making the transfer convinces Red that he isn’t the mole.
Making the connection between the Good Samaritan’s victims and his own history of abuse as a child, Liz and Ressler head for Hoffman’s childhood home, where he’s forcing his elderly mother to watch him torture Wilkinson. After killing Hoffman, Liz warns Wilkinson that she will come after him if he ever abuses his wife again. Finally, as Red’s killing spree ends with Newton Phillips, the man who arranged the attempt on his life, Tom tries to convince Liz to move to Nebraska. But when Liz balks at joining Tom for his job interview, Red reappears at her home ready to help find the mole.